By K. M. Treves-Brown MA, Vet MB (Cantab) (auth.)
As aquaculture maintains to extend there's a desire for larger wisdom of medicinal remedies either for the prevention and remedy of affliction and for the industrial husbandry of fish. This e-book, the 1st of its variety, is written for a world readership. it's a reference guide for someone curious about the choice of medications for management to fish. it is going to even be valuable to directors serious about the criminal keep watch over of aquaculture.
the 1st half covers matters which have an effect on all medicine's tools of administering medications to fish, a few of the facets of protection and the appropriate laws in nations with vital aquacultural industries. next elements evaluation the variety of obtainable medicinal elements and current present wisdom of the pharmacology and techniques of use for every. specific cognizance is given to issues of safety - for the fish, for the individual administering the medication, for the shopper of medicated fish and for the environment.
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Additional resources for Applied Fish Pharmacology
A specific example of a fish medicine having direct toxicity to non-target species is furazolidone which is extremely toxic to crustacea. Two points should be noted about the induction of antibiotic resistance. In the first place this is only a hazard if the micro-organisms in which resistance is induced are potential pathogens, either of Man or of other fauna which Man is likely to want to treat with antibiotics, or if there is a significant risk of the resistance being transferable to such potential pathogens.
2 ILLEGAL USE In addition to off-label use within its strict meaning, there is also considerable medicinal use in fish of substances which are not the subject of any MA at all. Although fumagillin has been studied for its possible use against proliferative kidney disease in rainbow trout, the standard drug for this widespread disease is malachite green. Artificial breeding is practised in virtually all species of fish husbanded intensively (see Chapter 17) and this nearly always involves the use of hormones.
In the USA the Centre for Veterinary Medicines (CVM) of the Food and Drug Administration (FDA) at one time published an 'Enforcement Guide' indicating conditions under which FDA would not normally object to extra-label use (Geyer, 1992). This Guide had no statutory authority and in 1994 it was replaced by the Animal Medicinal Drug Use Clarification Act (AMDUCA) which, in effect, decriminalized extra-label use by veterinarians. It nevertheless makes veterinarians responsible for ensuring that there are no consumer safety violations.